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2004 APR 7 - (NewsRx.com & NewsRx.net) -- A genetically engineered vaccine aimed at preventing tuberculosis was administered to volunteers at St. Louis University, part of a clinical trial that is the first-ever human testing of the vaccine known as rBCG30.
Some 2 billion people, about one-third of the world's population, are believed infected with the TB pathogen. About 2 million people die annually and the World Health Organization estimates that TB deaths will reach 36 million over the next 2 decades. TB is the leading killer of people with AIDS.
An existing vaccine that has been in use for decades is most useful to protect infants, but the effectiveness wears off as people age.
The rBCG30 vaccine being tested at St. Louis University has been more successful in preliminary tests, university officials said. Dr. Daniel F. ...
Source: HighBeam Research, New TB vaccine now in Phase I tests.