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2004 APR 1 - (NewsRx.com & NewsRx.net) -- Sublingual misoprostol is better than oral delivery for cervical priming.
"The aim of the study was to compare the effect of oral and sublingual administration of misoprostol for cervical priming prior to vacuum aspiration. Thirty-two first-time-pregnant women with 8 - 12 weeks amenorrhea were randomly assigned to receive 400 microgram misoprostol either orally or sublingually 3 hours prior to surgery. The degree of baseline dilatation and the cumulative force needed for dilatation of the cervical canal did not differ between the two treatment groups," scientists writing in the journal Contraception report.
"However, the number of patients in whom a strong force was needed was significantly higher following oral than following sublingual treatment," wrote A. Aronsson and colleagues, Karolinska Institute, Division of Obstetrics & Gynecology.
"It was shown that sublingual administration is more effective than oral ...
Source: HighBeam Research, Sublingual misoprostol is better than oral delivery for cervical...