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Vitamin D effects seasonal changes in serum 250HD levels in older women.

Women's Health Weekly

| April 01, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 APR 1 - (NewsRx.com & NewsRx.net) -- Vitamin D effects seasonal changes in serum 250HD levels in older women.

"Vitamin D-2 and D-3 are generally considered equipotent in humans. A few studies have reported that serum 25OHD levels are higher in vitamin D-3- compared with vitamin D-2-supplemented subjects. As both vitamin D-2 and D-3 supplements are commonly used by elderly in United States, in the present study we determined the effect of self-reported vitamin D-2 and vitamin D-3 supplement use on serum total 25OHD levels according to season in elderly women aged 65-77 years," investigators in the United States report.

"Serum total 25OHD levels were determined in winter and summer in unsupplemented women (n=307) and in women who reported taking vitamin D-2 (n=56) and vitamin D-3 (n=55) supplements by competitive protein binding assay. In vitamin D-2-supplemented women, the contribution of vitamin D-2 and D-3 to the mean serum total 25OHD level was assessed by HPLC," said P.B. Rapuri and colleagues, Creighton University, School of Medicine.

"In summer, there were no significant differences in the mean total serum 25OHD levels (ng/ml) among the vitamin D-2 (32[+ or -]2.1), vitamin D-3 (36.7[+ or -]1.95), and unsupplemented (32.2[+ or -]0.95) groups. In winter, the mean serum total 25OHD levels were higher in women on vitamin D-2 (33.6[+ or -]2.34, p

"In vitamin D-2-supplemented ...

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