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Proton therapy offers advantages for children with brain tumors, study shows.
2004 APR 1 - (NewsRx.com & NewsRx.net) -- Proton beam therapy offers a clear advantage over both conventional external beam radiation therapy and intensity modulated radiation therapy for treatment of the posterior fossa and spinal column in children with brain tumors, according to a study in the March 1, 2004, issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO, the American Society for Therapeutic Radiology and Oncology.
Advances in treatment methods for medulloblastoma - malignant tumors that develop in the cerebella - have led to increased survival rates for children affected by this disease.
Now that more and more children are surviving this disease, researchers are investigating ways to reduce the side effects from the standard combination of surgery, external beam radiation and chemotherapy.
This study compares the plans for three methods of treating the craniospinal axis in children with medulloblastoma in an effort to establish a more sophisticated radiation beam delivery that reduces radiation doses to nearby brain tissues.
The study examines side-by-side the isodose distributions and dose-volume histograms of target and nontarget sites of IMRT and proton treatment plans with those from a conventional external beam therapy plan.
In the first treatment plan, the study used conventional radiation beams to treat the craniospinal axis irradiation with a boost of radiation to the posterior fossa. The second plan consisted of whole-brain irradiation with conventional external radiation and IMRT.
The third used whole-brain irradiation using proton fields matched ...
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Source: HighBeam Research, Proton therapy offers advantages for children with brain tumors,...