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Diphtheria-tetanus-pertussis vaccine booster effective in adults.
2004 MAR 31 - (NewsRx.com & NewsRx.net) -- A diphtheria-tetanus-acellular pertussis vaccine booster was effective at increasing immunity in adults.
According to recent research published in the journal Vaccine, "Two clinical studies were undertaken to evaluate the immunogenicity of an adult-type dTpa booster vaccine (Boostrix by Glaxo-SmithKline Biologicals). Blood samples taken prior to vaccination showed that 24.4 and 13.0% of subjects were seronegative for diphtheria and tetanus antibodies, respectively. Moreover, about one-third of the vaccinees had no detectable levels of antibodies to pertussis toxoid (PT) or pertactin (PRN)."
"One month post-vaccination, more than 93% of all individuals, regardless of age or type of vaccine received, had seroprotective antibody levels for diphtheria and tetanus (greater than or equal to0.1 IU/mL)," reported Pierre Van Damme at the University of Antwerp in Belgium and Margaret Burgess at the University of Sydney in Australia. "In those individuals vaccinated with the adult-type dTpa vaccine (Boostrix), more than 98% were found to be seropositive for antibodies to all three pertussis antigens (PT, filamentous hemagglutinin (FHA), and PRN)."
"These data suggest that immunity to diphtheria, tetanus, and ...
- Diphtheria-tetanus-pertussis vaccine booster effective in adults.
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Source: HighBeam Research, Diphtheria-tetanus-pertussis vaccine booster effective in adults.