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Arch Dis Child Fetal Neonatal Ed 2004;89:F108-F111. doi: 10.1136/adc.2001.004275
Preterm birth requires rapid adaptation from a liquid to a gaseous, low humidity environment. There are several ways in which this can be facilitated. The management of sodium and water balance is considered here.
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The extremely immature infant below 26 weeks gestation is 80-90% water. (1) In utero, the baby is immersed in fluid, the lungs are filled with liquid, the skin is porous and lacking a keratin layer; urine output is high, and renal concentrating ability is limited. Preterm birth requires adaptation to an abrupt introduction to a gaseous, low ...