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Study of 196 women: HT patch has less impact on coagulation factors.(Gynecology)
SAN DIEGO -- Hormone therapy administered transdermally had significantly less impact on coagulation factors than did the same therapy given orally over 6 months in a study of 196 women.
The study was not designed to investigate whether thromboembolic events actually occurred less frequently in the women who used the transdermal approach. But laboratory values suggest that patch hormone therapy (HT) may be safer, said Dr. Karine Lacut of the department of internal medicine, Cavale Blanche Hospital, Brest, France.
Most notably, prothrombin fragment 1 and 2 levels increased, and fibrinogen levels decreased, in patients on oral therapy but not in those on ...
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