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Results announced for TA-1790 phase II head-to-head study with Viagra.

Women's Health Weekly

| March 04, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 MAR 4 - (NewsRx.com & NewsRx.net) -- VIVU.S., Inc., (VVU.S.) announced data on TA-1790, its oral phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED).

The phase II head-to-head at-home study comparing the onset of action between TA-1790 and Pfizer's (PFE) Viagra (sildenafil) showed comparable results. With each product, subjects had erections sufficient to achieve vaginal penetration on approximately 80% of attempts. These successful attempts occurred, on average, within 20 minutes after dosing.

This double-blind, randomized, crossover study in the home setting provides additional data to complement the earlier trial in the clinical setting (the in-clinic RigiScan efficacy trial results announced June 2003).

The efficacy demonstrated by TA-1790 in this at-home trial continues to support the rapid absorption and onset of action seen in the earlier in-clinic trial; however, it did not out-perform Viagra as it did in the in-clinic study.

"TA-1790's onset of action was consistently strong in both the at-home and in-clinic studies," said John Dietrich, PhD vice president of research and development for VIVU.S.

"These data and our belief in the overall safety profile of TA-1790 support our plans to continue the TA-1790 clinical development ...

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Source: HighBeam Research, Results announced for TA-1790 phase II head-to-head study with Viagra.

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