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Systematic analyses of randomized trials show dose and effect rule mifepristone.
2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Systematic analyses of randomized trials show dose and effect rule mifepristone.
"There is some evidence from randomized trials that different doses of mifepristone for emergency contraception do not differ in efficacy in the range from 10 mg to 600 mg. Lower doses have a better side effect profile and are cheaper and therefore they would be preferable in the absence of a dose effect. However, the lack of significance is not evidence of absence of an effect," researchers in Switzerland report.
"More evidence can be obtained by combining results of trials. We present meta-analyses of randomized trials comparing doses of mifepristone for emergency contraception from 5 mg to 600 mg, with regard to the efficacy to prevent unwanted pregnancies. We use two approaches for analysis, one using only within-trial information and another one combining within-trial with between-trial information," G. Piaggio and colleagues, World Health Organization, Department of Reproductive Health and Research said.
"We discuss the results in terms of equivalence. There is some evidence of a small dose effect on efficacy in the lower range of doses (
"In terms of the number of women ...
- Randomized trials study low-fat vs low-carbohydrate diets for weight loss.
- Magazine article from: Women's Health Weekly June 17, 2004 700+ words
...amp; NewsRx.net) -- Two randomized trials of low-fat versus low-carbohydrate...article was prepared by Women's Health Weekly editors from staff and other...Copyright 2004, Women's Health Weekly via NewsRx.com & NewsRx...
- Randomized trials and quasi-experiments in education research.(Research...
- Magazine article from: NBER Reporter Angrist, Joshua D. June 22, 2003 700+ words
...Education put studies involving randomized trials and quasi-experiments...methodological hierarchy. Randomized trials are experiments in which...software is expensive). Randomized trials provide the best scientific...
- Comparing drug effectiveness at health plans: the ethics of cluster randomized...
- Magazine article from: The Hastings Center Report Sabin, James E. Mazor, Kathleen Meterko, Vanessa Goff, Sarah L. Platt, Richard September 1, 2008 700+ words
"Cluster randomized trials," in which groups of patients...80 million. Conventional randomized trials often have two additional drawbacks...typically excluded from conventional randomized trials. Also, the process of obtaining...
- Place Randomized Trials: Experimental Tests of Public Policy.(SOCIAL SCIENCES...
- Magazine article from: Reference & Research Book News August 1, 2005 700+ words
...4129-2581-9 Place randomized trials; experimental tests of...291 p. $46.00 Place randomized trials can be used to gather evidence...evaluate the use of place randomized trials in the context of evaluating...
- What kind of randomized trials do we need?
- Magazine article from: Canadian Medical Association. Journal Zwarenstein, Merrick; Treweek, Shaun May 12, 2009 700+ words
...argued that there are 2 kinds of randomized trials embodying radically different attitudes...decisions and the clinical context of the randomized trials that they must use for evidence means...fewer than 100 pragmatic designed randomized trials, of the quarter million or so RCTs...
- Evaluation of published group-randomized trials show inappropriate analysis.
- Newspaper article from: Clinical Oncology Week April 26, 2004 700+ words
...published data from group-randomized trials show some inappropriate analysis has been reported. Group-randomized trials (GRTs) "published in the...Design and analysis of group-randomized trials: A review of recent practices...
- Use of placebos in randomized trials unethical.
- Newspaper article from: Medical Letter on the CDC & FDA June 1, 2003 700+ words
...com & NewsRx.net) -- The use of placebos in randomized trials often is unethical, say two researchers at Harvard University...Declaration and the common practice of using placebo controls in randomized trials even if effective treatment exists." "Despite the mandates...
- Optimal permutation tests for the analysis of group randomized...
- Magazine article from: Journal of the American Statistical Association Braun, Thomas M. Feng, Ziding December 1, 2001 700+ words
...facts complicate the comparison of interventions in group randomized trials (GRT's), a family of clinical trials in which each...WWT belong to a class of clinical trials known as group randomized trials (GRT's), in which each member of a particular group...
