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2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Determining breast density by mammography may be helpful in assessing breast cancer risk, researchers report.
According to a study from the United States, "Increased mammographic breast density is a moderate independent risk factor for breast cancer, with findings of published studies in which quantitative methods of assessment were used showing a positive association. Breast density may be quantified by using visual assessment or planimetry."
"Although the category definitions vary, the odds ratio for developing breast cancer for the most dense compared with the least dense breast tissue categories ranges from 1.8 to 6.0, with most studies yielding an odds ratio of 4.0 or greater," wrote J.A. Harvey and colleagues, University of Virginia, Department of Radiology.
"Plausible explanations for the association of breast density with increased breast cancer risk may be the development of premalignant lesions such as atypical ductal hyperplasia, elevated growth factors, or increased estrogen production within the breast due to overactive aromatase," the researchers wrote.
The amount of breast ...
Source: HighBeam Research, Higher breast density is associated with increased breast cancer risk.