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Gastrointestinal side effects from alendronate require additional medication.
2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Gastrointestinal side effects from alendronate require additional medication.
According to research from Turkey, "the aim of our study was to evaluate the upper gastrointestinal (GI) tract side effect profile in 759 female patients that had taken alendronate (10 mg/day), for at least 6 months, for the treatment of osteoporosis, in relation to the safety of alendronate and the compliance of patients to its absorption rules. This study was a multicentered retrospective, clinical, non-placebo controlled, study of 759 female subjects carried out at 26 centers in 6 different regions of Turkey."
"The mean age of our patients was 62.6[+ or -]8.6, with 51.2% in the age range 60 to 69 years. 158 patients (20.8%) were considered to have upper GI tract complaints with nausea as the most often encountered symptom. Of the subjects with upper GI tract complaints, 20% reported discontinued drug use, and 30% reported the requirement of an additional drug in order to abolish their complaints," S. Aki and colleagues, Istanbul University, Medical Faculty, Department of Physical Medicine and Rehabilitation wrote.
"Approximately 537 (71%) of the patients stated they had been given written information about the administration of the ...
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Source: HighBeam Research, Gastrointestinal side effects from alendronate require additional...