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Cucumber mosaic virus as carrier of a hepatitis C virus-derived epitope.
2004 MAR 3 - (NewsRx.com & NewsRx.net) -- The cucumber mosaic virus can be used as a carrier of a hepatitis C virus-derived epitope.
"Cucumber mosaic virus (CMV) is a three component isodiametric plant virus which is common worldwide and has an extremely wide host range. A pseudorecombinant was made, derived from the RNA3 component of the CMV-S strain, carrying the coat protein (CP) gene, and the RNA1,2 components of the CMV-D strain. This system developed mild mosaic and vein clearing in Xanthi tobacco three weeks after inoculation," scientists in Italy report.
"The CP gene was then engineered in three different positions, to encode a hepatitis C virus (HCV) epitope," said A. Natilla and collaborators at the Universita Degli Studi della Basilicata and Universita Degli Studi di Bari. "The selected peptide was the so-called R9 mimotope, a synthetic surrogate derived from a consensus profile of many hypervariable region 1 (HVR1) sequences of the putative HCV envelope protein E2. Serum samples from 60 patients with chronic hepatitis C displayed a significant immunoreactivity to crude plant extracts ...
- Universita' Degli Studi di Bologna obtains United States patent.(Brief Article)
- Newspaper article from: BIOTECH Patent News October 1, 2002 700+ words
Universita' Degli Studi di Bologna (Bologna, Italy) and Inserm Institut National de la Sante et de la Recherche Medicale (Paris, France) have patented...
- Universita degli Studi di Roma obtains United States patent.(Brief article)
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Universita degli Studi di Roma "La Sapienza" (Italy) has patented a nucleotide sequence encoding for a protein characterized in that it has a silencing...
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...diabetes mellitus and pathologies associated with protein aggregation phenomena. The patent has been assigned to Universita' degli Studi di Firenze, Firenze, Italy. According to an abstract posted by the World Intellectual Property Organization...
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...from Italy, have developed a method for detection of the healthy carrier state. The patent has been assigned to Universita degli Studi di Trieste, Trieste, Italy, Istituto di Ricovero e Cura a Carattere Scientifico Pediatrico Burlo Garofolo...
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...Luca Guandalini - all from Italy, have developed novel antineoplastic agents. The patent has been assigned to Universita degli Studi di Firenze, Firenze, Italy, and A.I.L. Firenze Sezione autonoma di Firenze dell'Associazione Italiana...
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- News wire article from: US Fed News Service, Including US State News August 28, 2009 700+ words
...yeast. The inventors were issued U.S. Patent No. 7,579,171 on Aug. 25. The patent has been assigned to Universita Degli Studi Di Milano Bicocca, Milan, Italy. According to the abstract released by the U.S. Patent & Trademark...
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...have developed cassettes containing Arabidopsis thaliana CYP86A2 gene promoter. The patent has been assigned to Universita degli Studi di Milano, Milano, Italy. According to an abstract posted by the World Intellectual Property Organization...