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DNA vaccine more effective against rabies than culture-derived vaccine.
2004 FEB 11 - (NewsRx.com & NewsRx.net) -- A single injection of DNA vaccine is as effective against postexposure rabies as five injections of cell culture-derived vaccine.
"Two rabies post-exposure therapies were comparatively evaluated: BALB/c mice were challenged at day 0 with rabies virus and then received either a single dose of rabies DNA vaccine administered at day 0, or 5 doses of cell culture-derived rabies vaccine administered at days 0, 3, 7, 15, and 28. Both regimens rapidly triggered protective levels of neutralizing antibodies against rabies virus in vaccinated mice. In addition, one injection of DNA vaccine protected 53% of the challenged mice, compared to 40% of mice protected after five injections of cell culture-derived vaccine," scientists writing in the journal Vaccine report.
"We conclude that rabies post-exposure vaccination in BALB/c mice, based on a single administration of rabies DNA vaccine might be at least as effective as five injections of cell culture-derived vaccine," reported Chokri Bahloul and colleagues at ...
- DNA vaccine more effective against rabies than culture-derived vaccine.
- Newspaper article from: Drug Week February 13, 2004 700+ words
...single injection of DNA vaccine is as effective...cell culture-derived vaccine. "Two rabies...administration of rabies DNA vaccine might be at least...cell culture-derived vaccine," reported Chokri...single injection of DNA vaccine is as effective...cell ...
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