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Researchers create new animal model for testing AIDS drugs. (North Carolina State University) (SCID mice) (Informative Briefs From Worldwide Sources)
North Carolina
Researchers at the North Carolina State University (NCSU) College of Veterinary Medicine and Burroughs Wellcome Company have developed a new small-animal model for use in screening and identifying drugs that can combat HIV.
The model was created by engrafting immune system cells from cats into a breed of mouse that lacks a functioning immune system. The mice, known as SCID mice, are born with severe combined immunodeficiency disease, a condition that strips them of their natural immune defenses.
The effect of the transplant, the researchers say, is to establish a functioning feline immune system in the mice. The mice are subsequently injected with feline immunodeficiency virus (FIV), which infects the animals by targeting specific …
