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HIV genital tract shedding linked to plasma viremia.
2004 FEB 5 - (NewsRx.com & NewsRx.net) -- HIV genital tract shedding is correlated with plasma viremia.
In a recent study, researchers "examined 30 HIV-infected women in Manila to assess the relationship between cervicovaginal and plasma HIV-1 viral load."
"An interview and gynecologic examination was conducted and cervicovaginal lavage (CVL) and venous blood specimens were collected," explained G.U. Natividad-Villanueva and coauthors affiliated with Brown University in Providence, Rhode Island.
"HIV-1 RNA was detected in plasma samples of 24 patients (80%) and in CVL samples of 18 women (60%); 16 patients (53%) had detectable levels in both," test results indicated. "CVL HIV-1 RNA was detectable in 75% of women (6/8) with plasma viral loads between 10,000-100,000 copies/mL and in 77% of women (10/13) with plasma viral loads >100,000 copies/mL (p=0.0086)."
"Among women with CD4 cell counts of <200, 200-500, and>500/mm[superscript]3, CVL HIV-1 RNA was detected in 73%, 69%, and 17% of women, ...
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Source: HighBeam Research, HIV genital tract shedding linked to plasma viremia.