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Keynote address on Xyotax delivered at polymer therapeutics meeting.
2004 FEB 5 - (NewsRx.com & NewsRx.net) -- At the 6th International Symposium on Polymer Therapeutics in Cardiff, Wales, Cell Therapeutics, Inc., (CTIC, CTI) was honored with a keynote presentation on Xyotax, CTI's drug candidate that links paclitaxel, the active chemotherapy agent used in Taxol, to a water soluble, biodegradable, polyglutamate polymer.
In his keynote address, Jack W. Singer, MD, VP, and research chair at CTI explained that Xyotax was developed to provide a potentially more effective treatment with fewer toxicities. To date, more than 1200 patients have been treated with Xyotax in clinical trials.
"Based on data from preclinical studies it appears that Xyotax patients have approximately 100 times less free paclitaxel in their blood stream than patients receiving an equivalent dose of marketed paclitaxel products," said Singer. "This unique profile may be responsible for the lack of hair loss and the markedly lower incidence of severe neutropenia observed in clinical studies with Xyotax."
Singer explained that data from nonclinical studies show that ...
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Source: HighBeam Research, Keynote address on Xyotax delivered at polymer therapeutics meeting.