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2004 FEB 5 - (NewsRx.com & NewsRx.net) -- More than 60% of microcalcifications in comedo-type intraductal carcinoma can be demonstrated by ultrasound, researchers say.
According to published research from Taiwan, "The purpose of this study is to evaluate the diagnostic ability of ultrasound and define the sonographic features of symptomatic intraductal and invasive breast carcinoma. To achieve this the ultrasound features of 488 invasive carcinomas and 65 non-screening detected intraductal carcinomas were compared retrospectively.
"The features included size, AP/W (anteroposterior diameter/width) ratio, shape, margin, internal echogenicity, internal echotexture, posterior acoustic transmission, bilateral edge shadowing sign and calcifications," wrote S.C. Chen and colleagues, Chang Gung University, Chang Gung Memorial Hospital.
"The sensitivity and specificity of the detection of calcifications by ultrasound in comparison with mammography were also studied. The accuracy of ultrasound diagnosis is 92.0% for invasive carcinoma of the breast and 84.8% for intraductal carcinoma," the researchers wrote.
"Differentiation of ultrasound features of intraductal and invasive carcinoma can be based on the internal hypoechogenicity, loss of bilateral edge shadowing, posterior acoustic transmission, irregular shape and nonuniform internal echotexture with odds ratio of 0.3, 0.3, 0.4, 0.5, and 0.5, respectively," the researchers stated.
"Internal echogenicity was the only significant differentiating factor on multiple logistic regression analysis. Noncomedo-type ductal carcinoma in situ can be ...