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Interviews alone can't predict polycystic ovary syndrome status.

Women's Health Weekly

| February 05, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 FEB 5 - (NewsRx.com & NewsRx.net) -- Interviews alone can't predict polycystic ovary syndrome status.

"Polycystic ovary syndrome (PCOS), a leading cause of female infertility, occurs in approximately 4% of women of reproductive age. Multifamily studies have established that PCOS has strong inherited traits. Although diagnosis of PCOS in the relatives of affected women can readily be made by clinical and biochemical evaluations, these methods are costly and laborious," investigators in the United States report.

"The aim of this investigation was to determine whether clinically evident PCOS could be detected by a written questionnaire, which is a significantly less expensive means of detection than direct determination. A questionnaire about the history of possible androgenic symptoms of PCOS was presented to patients and their first-degree female relatives, who were also evaluated by physical and laboratory examinations. The sensitivity, specificity, and positive predictive value (PPV) and negative predictive value (NPV) for the detection of PCOS by interview were calculated," wrote M.D. Kahsar-Miller and colleagues, Cedars Sinai Medical Center, Department of Obstetrics & Gynecology.

"The NPV of the proband interview was significantly lower for sisters than for mothers (82% vs. 100%, respectively; p <0.05). When the family member completed the written questionnaire directly, the specificity and NPV of self-reporting were equally high (>90%) ...

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Source: HighBeam Research, Interviews alone can't predict polycystic ovary syndrome status.

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