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Leading AIDS experts criticize U.S.-sponsored HIV vaccine trial in Thailand.
2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Several national AIDS experts criticized a U.S. government-sponsored clinical research trial of an AIDS vaccine in Thailand in a recent journal report.
The 22 researchers said that there are no "persuasive data" to suggest that the experimental vaccine, a combination of ALVAC +gp120, would help to protect against HIV infection. The research trial involves 16,000 volunteers in Thailand.
The scientists, writing in Science, said that a clinical trial of similar design was scheduled to be conducted in the United States by the HIV Vaccine Trials Network (HVTN), the world's largest consortium of AIDS vaccine scientists and clinicians, but was cancelled in 2003 because earlier trials had yielded weak results in terms of immune response to the vaccines.
Vaccines work by inoculating people with a small amount of a virus or portion of a virus to produce an immune response. The vaccine primes the body to recognize and fight the infection should the person be exposed to it in the future.
The Thailand clinical trial seeks to test the effectiveness of a vaccine made from a protein found on the surface of the AIDS virus, called gp120, when given in combination with ALVAC, a vaccine composed of a ...
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Source: HighBeam Research, Leading AIDS experts criticize U.S.-sponsored HIV vaccine trial in...