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Tumor cells plus adjuvant induced immunity against hepatoma.
2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Fixed tumor cells in combination with adjuvant induced protective antitumor immunity in a murine hepatoma model.
According to recent research published in the journal Cancer Letters, "We previously reported that fixed tumor sections induced autologous cytotoxic T lymphocytes (CTL) from human peripheral blood lymphocytes in vitro. Here, we examined whether fixed tumor cells could stimulate in vivo immunity using a murine hepatoma model."
"Vaccination of syngeneic mice with fixed Hepa 1-6 cells in combination with OK-432 and tuberculin as an adjuvant resulted in a significant increase in survival of mice against live Hepa 1-6 cell challenge," said Lan Huang and Tadao Ohno at the Institute of Physical and Chemical Research (RIKEN). "In addition, the splenocytes from vaccinated mice secreted CD4+ T cell-mediated interferon-gamma (IFN-gamma) and exhibited a specific CTL response. These findings suggest that fixed tumor cells combined with an ...
- Tumor cells plus adjuvant induced immunity against hepatoma.
- Newspaper article from: Cancer Vaccine Week February 2, 2004 700+ words
...net) -- Fixed tumor cells in combination...in the journal Cancer Letters, "We previously...suggest that fixed tumor cells combined with...their study in Cancer Letters (Protective...induced by fixed tumor cells in combination...
- Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast...
- Newspaper article from: Clinical Oncology Alert November 1, 2004 700+ words
Circulating Tumor Cells, Disease Progression, and Survival...Synopsis: The number of circulating tumor cells before treatment is an independent...breast cancer for levels of circulating tumor cells both before and after the initiation...
- Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast...
- Newspaper article from: Clinical Oncology Alert October 1, 2004 700+ words
Circulating Tumor Cells, Disease Progression, and Survival...Synopsis: The levels of circulating tumor cells at baseline and at the first follow...breast cancer for levels of circulating tumor cells both before and after the initiation...
- Aphton Reports Activity of IGN101 in Reducing Disseminating Tumor Cells From...
- Press release article from: Business Wire May 16, 2005 700+ words
...ability of IGN101 to decrease circulating tumor cells in peripheral blood. Elevation of circulating tumor cells has been shown to predict short survival...29 and 57. Analyses of circulating tumor cells in peripheral blood were performed on...
- Level of Circulating Tumor Cells in Bloodstream Predicts Breast Cancer...
- Press release article from: PR Newswire August 18, 2004 700+ words
...the body, the level of circulating tumor cells in the bloodstream before treatment...suggest that the presence of circulating tumor cells can shed light on the prognosis of patients...technology may allow the examination of tumor cells by simply drawing blood, opening up...
- Quest Diagnostics to Offer New Test to Measure Circulating Tumor Cells in...
- Press release article from: PR Newswire September 20, 2004 700+ words
...that identifies and counts circulating tumor cells in blood samples from patients being...demonstrated that the number of circulating tumor cells is predictive of progression free survival...used for the enumeration of circulating tumor cells of epithelial origin in whole blood...
- Enzymatic cleavage of CD95 leaves tumor cells resistant to destruction.
- Newspaper article from: Biotech Week July 7, 2004 700+ words
...Enzymatic cleavage of CD95 leaves tumor cells resistant to destruction. "The ability of tumor cells to resist apoptosis-inducing signals...independent cytotoxic T-cell killing of tumor cells. We propose a new strategy by which...
- Applied Imaging and StemCell Technologies Renew Exclusive Agreement to Supply...
- Press release article from: PR Newswire July 20, 2004 700+ words
...the isolation of circulating tumor cells in the blood of cancer patients...isolation and analysis of circulating tumor cells, frequently associated with...technology, enriches circulating tumor cells directly from samples of cancer...
Source: HighBeam Research, Tumor cells plus adjuvant induced immunity against hepatoma.