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Tomato parasite shares antigens with Trypanosoma cruzi.
2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Phytomonas serpens, a tomato parasite, shares antigens with Trypanosoma cruzi that are recognized by human sera and induce protective immunity in mice.
According to published research from Brazil, "The immune cross-reactivity between Trypanosoma cruzi, the protozoan that causes Chagas' disease, and Phytomonas serpens, a trypanosomatid that infects tomatoes, was studied. Sera from patients with Chagas' disease presented a strong reactivity with P. serpens antigens by conventional serological assays such as indirect immunofluorescence (IIF) and direct agglutination test (DAT), confirmed after cross-absorption experiments."
"The results show that this protozoan is highly immunogenic and that rabbit and mouse hyperimmune serum raised against T. cruzi or P. serpens was able to recognize both T. cruzi and P. serpens antigens in immunofluorescence and agglutination assays," reported Jose Wander Bregano at the Universidade Estadual de Londrina and collaborators in Brazil. "The antigenic cross-reactivity between T. cruzi and P. serpens was also demonstrated in vivo. BALB/c mice immunized by the intraperitoneal or oral route with P. serpens and later challenged with a lethal inoculum of T. cruzi blood forms showed a significant decrease in parasitemia and increase in survival compared to ...
- Tomato parasite shares antigens with Trypanosoma cruzi.
- Newspaper article from: Biotech Week February 4, 2004 700+ words
...reactivity between Trypanosoma cruzi, the protozoan...Immunology and Medical Microbiology (Phytomonas serpens...antigens with Trypanosoma cruzi that are recognized...Immunology and Medical Microbiology can be contacted...
- Trypanosoma cruzi and the Trypanosoma cruzi and the United States Blood Supply:...
- Newspaper article from: Travel Medicine Advisor February 1, 2004 700+ words
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- Trypanosoma cruzi proteinase protects against trypanosomiasis.
- Newspaper article from: Vaccine Weekly November 6, 2002 700+ words
...writer - The major proteinase of Trypanosoma cruzi, cruzipain, showed promise as a...mucosal and systemic protection against Trypanosoma cruzi in mice. Infect Immun, 2002;70...reproduction when cocultured with Trypanosoma cruzi-infected macrophages * Mice immunized...
- Trypanosoma cruzi antigens elicit strong humoral immune response in mice.
- Newspaper article from: Immunotherapy Weekly December 3, 2003 700+ words
...and flagellar repetitive antigen of Trypanosoma cruzi elicited a strong humoral immune...flagellar repetitive antigen (FRA) of Trypanosoma cruzi. The immunization was done by subcutaneous...and flagellar repetitive antigen of Trypanosoma cruzi. Mem Inst Oswaldo Cruz, 2003...
- Trypanosoma cruzi in Guatemalan children linked to thatched roofs.
- Newspaper article from: Drug Week September 12, 2003 700+ words
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- Trypanosoma cruzi, T. rangeli is distinguishable by PCR in human, insect.
- Newspaper article from: TB & Outbreaks Week November 25, 2003 700+ words
...crossreacting assay can distinguish Trypanosoma cruzi from Trypansosoma rangeli from human...for the simultaneous detection of Trypanosoma cruzi and Trypanosoma rangeli in experimentally...Laboratory Immunology (Detection of Trypanosoma cruzi and Trypanosoma rangeli infection...
- Trypanosoma cruzi antigen and CpG-ODN protect against trypomastigotes.
- Newspaper article from: Health & Medicine Week April 26, 2004 700+ words
...amp; NewsRx.net) -- A purified Trypanosoma cruzi antigen and CpG oligodeoxynucleotides...the major cystein proteinase of Trypanosoma cruzi, in the process of parasite internalization...study in Vaccine (Use of a purified Trypanosoma cruzi antigen and CpG oligodeoxynucleotides...
- Trypanosoma cruzi in persons without serologic evidence of disease,...
- Magazine article from: Emerging Infectious Diseases Salomone, Oscar A. Basquiera, Ana L. Sembaj, Adela Aguerri, Ana M. Reyes, Maria E. Omelianuk, Mirtha Fernandez, Ruth A. Enders, Julio Palma, Atilio Barral, Jose Moreno Madoery, Roberto J. December 1, 2003 700+ words
...specific immunoglobulin G against Trypanosoma cruzi. However, the presence of parasites...of immunoglobulin (Ig) G against Trypanosoma cruzi by more than two different serologic...11). PCR for Identification of Trypanosoma cruzi Peripheral blood samples were drawn...
