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Vibrio cholerae toxins activate proinflammatory immune response.

Vaccine Weekly

| January 21, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Vibrio cholerae toxins activate the proinflammatory immune response.

According to recent research from the United States, "Vibrio cholerae induces either non-inflammatory diarrhea or inflammatory gastroenteritis, depending on the presence of cholera toxin, a fluid secretion inducer and a modulator of host immunity."

"In the absence of cholera toxin, other toxins induce inflammation, resulting in gastroenteritis," stated Karla J. Fullner Satchell at Northwestern University. "Thus, multiple toxins likely affect the safety of live attenuated vaccines."

Satchell published her study in Microbes and Infection (Activation and suppression of the proinflammatory immune response by Vibrio cholerae ...

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Source: HighBeam Research, Vibrio cholerae toxins activate proinflammatory immune response.

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