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ELISA and virus neutralization assay yield same measles antibody titers.
2004 JAN 21 - (NewsRx.com & NewsRx.net) -- The enzyme-linked immunosorbent assay and virus neutralization assay yield similar values for measles virus-specific antibody titers.
According to recent research from the Netherlands, "We assessed whether measles virus-specific antibody levels in the Dutch population as estimated by an enzyme-linked immunosorbent assay (ELISA) were comparable with estimates by virus neutralization assay (NT), prompted by a relatively low ELISA seroprevalence in the 10- to 21-year-old group. We tested 791 sera from individuals aged 2-49 years both in ELISA and NT."
"Seroprevalence in the 10- to 21-year-old group was 93.4% (95% confidence interval (CI) 89.5-97.2%) in ELISA versus 97.2% (CI 94.7-99.6%) in NT," reported Susan van den Hof and colleagues at the National Institute of Public Health and the Environment in Bilthoven. "There was good agreement between virus neutralization assay and ELISA seroprevalences in the vaccinated 2-to 9-year-olds ...
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Source: HighBeam Research, ELISA and virus neutralization assay yield same measles antibody...