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Nasal spray flu vaccine may help prevent influenza in healthy children.

Vaccine Weekly

| January 21, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JAN 21 - (NewsRx.com & NewsRx.net) -- An influenza virus vaccine delivered as a nasal spray, appears to be effective in protecting healthy children against certain strains of influenza, according to a new study.

Each winter, influenza causes significant illness in all age groups, according to the study. The U.S. Food and Drug Administration recently approved an influenza virus vaccine (cold-adapted trivalent influenza virus vaccine, or CAIV-T) administered in the form of a nasal spray for use in healthy children and adults aged 5-49 years. Previous studies have shown that the nasal spray was successful in preventing influenza A (H3N2) and B infections in children 15 months old to about 6 years old, and was effective in preventing certain strains of the influenza virus from infecting adults. However, the ability of CAIV-T to prevent natural influenza A (H1N1) infection is unknown.

Manjusha J. Gaglani, MBBS, from the Scott & White Memorial Hospital and Clinic, Temple, Texas, and colleagues assessed the effectiveness of CAIV-T in healthy children during the 2000-2001 influenza A (H1N1) epidemic. Their findings are published in the January 2004 issue of the Archives of Pediatrics & Adolescent Medicine.

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