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2004 JAN 21 - (NewsRx.com & NewsRx.net) -- An influenza virus vaccine delivered as a nasal spray, appears to be effective in protecting healthy children against certain strains of influenza, according to a new study.
Each winter, influenza causes significant illness in all age groups, according to the study. The U.S. Food and Drug Administration recently approved an influenza virus vaccine (cold-adapted trivalent influenza virus vaccine, or CAIV-T) administered in the form of a nasal spray for use in healthy children and adults aged 5-49 years. Previous studies have shown that the nasal spray was successful in preventing influenza A (H3N2) and B infections in children 15 months old to about 6 years old, and was effective in preventing certain strains of the influenza virus from infecting adults. However, the ability of CAIV-T to prevent natural influenza A (H1N1) infection is unknown.
Manjusha J. Gaglani, MBBS, from the Scott & White Memorial Hospital and Clinic, Temple, Texas, and colleagues assessed the effectiveness of CAIV-T in healthy children during the 2000-2001 influenza A (H1N1) epidemic. Their findings are published in the January 2004 issue of the Archives of Pediatrics & Adolescent Medicine.
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