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Flow cytometric assay for responses to anthrax vaccine developed.
2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Scientists have developed a flow cytometric assay using TNF-alpha detection to determine cellular responses to anthrax vaccine.
"This study describes a four-color flow cytometric assay that detects CD4+ T cell responses to the anthrax vaccine. Whole blood from seven volunteers who previously obtained the anthrax vaccine was inoculated in vitro with varying concentrations of the anthrax antigen. TNF-alpha and IFN-gamma production from memory CD4+ T cells were measured and compared to a control group who never received the anthrax vaccine," scientists in the United States report.
"The optimal antigen concentration for TNF-alpha was determined to be around 7.5 microgram/mL and IFN-gamma production was not detected," said Annie H. Shinn and collaborators at the University of the Pacific, Becton Dickinson Biosciences, and the Clinical Investigation Facility at Travis Air Force Base. "This assay will be used in future larger ...
- Flow cytometric assay for responses to anthrax vaccine developed.
- Newspaper article from: Drug Week January 23, 2004 700+ words
...responses to anthrax vaccine. "This study...color flow cytometric assay that detects...responses to the anthrax vaccine. Whole blood...using a flow cytometric assay to determine...responses to anthrax vaccine. J Immunol...
- Cell Signaling Technology and TTP LabTech Collaborate to Develop and Co-Market...
- Press release article from: Business Wire January 31, 2008 700+ words
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- VaxGen Awarded $80.3 Million NIAID Contract for Advanced Development of Anthrax...
- Press release article from: PR Newswire October 1, 2003 700+ words
...for the advanced development of its anthrax vaccine candidate, rPA102. The 3-year...contract for a national stockpile of anthrax vaccine. (Logo: http://www.newscom...recombinant Protective Antigen (rPA) anthrax vaccine, pending legislation known as Project...
- VaxGen Completes Development Activity in Support of Anthrax Vaccine Partnering...
- Press release article from: PR Newswire May 24, 2007 700+ words
...further development of its recombinant anthrax vaccine and is laying off 20 employees, or...support ongoing efforts to partner its anthrax vaccine program and was based on the Department...procurement of a next-generation anthrax vaccine. (Logo: NewsCom: http://www...
- Citizen Petition Filed Yesterday at the FDA: Anthrax Vaccine Network Supports...
- Press release article from: PR Newswire October 16, 2001 700+ words
...Michigan firm which manufactures the anthrax vaccine. The petition calls for the FDA to...on the drug category placement of anthrax vaccine as Category II (unsafe, ineffective...declare as adulterated all stockpiles of anthrax vaccine adsorbed in the possession of BioPort...
- VaxGen Responds to Media Report Regarding Proposed Congressional Investigation...
- Press release article from: PR Newswire April 6, 2006 700+ words
...investigation into the company's anthrax vaccine contract by Congressman Mike Rogers...investigation of our Project BioShield anthrax vaccine contract, because: -- The Department...contract for 75 million doses of a modern anthrax vaccine to VaxGen was the result of an open...
- Anthrax Vaccine Award Rescheduled to Nov. 5; VaxGen Believes It Is the Only...
- Press release article from: PR Newswire October 15, 2004 700+ words
...million doses of a recombinant anthrax vaccine to the U.S. government...VaxGen has been developing its anthrax vaccine candidate, rPA102, to address...for a modern recombinant anthrax vaccine, based on a single defined...
- Dynavax Anthrax Vaccine Induces High Antibody Responses and Shows Protection in...
- Press release article from: PR Newswire March 21, 2005 700+ words
...immunostimulatory sequence (ISS) based anthrax vaccine has the potential to confer...to the currently available anthrax vaccine and a prototype second-generation...Our novel, proprietary anthrax vaccine formulation has potential...
- Emergent BioSolutions Acquires Advanced Recombinant Protective Antigen Anthrax...
- Press release article from: Business Wire May 5, 2008 700+ words
...a domestic source for an advanced anthrax vaccine candidate to meet planned procurement...recombinant protective antigen (rPA) anthrax vaccine product candidate and related technology...procure 25 million doses of an rPA anthrax vaccine for the Strategic National Stockpile...
- VaxGen and BD to Jointly Evaluate Novel Dermal Injection Technology for...
- Press release article from: PR Newswire February 21, 2006 700+ words
...to deliver VaxGen's recombinant anthrax vaccine candidate. Funding will be provided...injection into the skin) of VaxGen's anthrax vaccine with the patented BD Micro Injection...technology in combination with VaxGen's anthrax vaccine proves safe and effective, and is...
Source: HighBeam Research, Flow cytometric assay for responses to anthrax vaccine developed.