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Liver enzymes may not reflect NASH in obese: morbid obesity.(News)

Internal Medicine News

| December 15, 2003 | Worcester, Sharon | COPYRIGHT 2008 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

BOSTON -- Don't rely on routine liver function tests to identify liver disease in morbidly obese patients, Dr. Patricia Latham warned at the annual meeting of the American Association for the Study of Liver Diseases.

Of 155 morbidly obese patients who underwent Roux-en-Y gastric bypass surgery and wedge liver biopsy during 2002, 20 were found to have nonalcoholic steatohepatitis (NASH), and of those, 15--including 1 with cirrhosis--had entirely normal liver enzyme levels, said Dr. Latham of George Washington University, Washington.

The patients in the study had a mean age of 38 years, and most (90%) were women. Patients with NASH had a mean age of 43 and a…

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