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Advances in tuberculosis research offer novel vaccine strategy insights.
2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Advances in antibody-mediated immunity against Mycobacterium tuberculosis have provided insights for developing novel vaccine strategies.
"Cell-mediated immunity is considered to be the major component of the host response against Mycobacterium tuberculosis, whereas antibody-mediated immunity historically has been considered inconsequential. In recent years, studies from several groups have challenged the traditional dogma and demonstrated that monoclonal antibodies can modify various aspects of mycobacterial infections," a scientist writing in the journal FEMS Immunology and Medical Microbiology reports.
"This review describes the experimental evidence supporting a role for antibodies in defense against mycobacterial infections and outlines future challenges to the field of antibody-mediated immunity against M. tuberculosis, with particular emphasis on the implications of these findings for a novel vaccine strategy," said Aharona Glatman-Freedman at Albert ...
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Source: HighBeam Research, Advances in tuberculosis research offer novel vaccine strategy...