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M protein gene subtypes from invasive group A streptococcus recovered.
2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers have recovered an array of M protein gene subtypes in invasive group A streptococcus isolates recovered from the active bacterial core surveillance.
According to recent research published in the Journal of Infectious Diseases, "Using sequence analysis to detect variation within the hypervariable M protein N terminus, we found 41 emm types encompassing 81 subtypes, among 1,064 consecutive invasive group A Streptococcus isolates from a recent multistate, population-based surveillance. Seventeen of the 30 emm types represented by multiple isolates displayed multiple subtypes."
"Most subtypes differed from reference strain emm sequences as a result of single base substitutions or other alterations likely to be stably inherited," reported Zhongya Li at the Centers for Disease Control and Prevention and fellow members of the Active Bacterial Core Surveillance/Emerging Infections Program Network. "The Centers for Disease Control and Prevention database (available at: http://www.cdc.gov/ncidod/biotech/strep/strepblast.htm) currently contains 225 distinct ...
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Source: HighBeam Research, M protein gene subtypes from invasive group A streptococcus recovered.