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Data reported in trials of heat shock protein-based cancer vaccines.
2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Antigenics, Inc., (AGEN) announced updated results from clinical trials of HSPPC-70 (previously referred to as AG-858) and Oncophage (HSPPC-96) personalized cancer vaccines, both of which are based on the company's proprietary heat shock protein (HSP) technology.
Preliminary data from a phase I study of HSPPC-70 in chronic myelogenous leukemia and from a phase II trial of Oncophage in non-Hodgkin lymphoma indicate that treatment with the HSP-based vaccines is well tolerated and feasible, and may be associated with clinical response. Findings were presented in separate poster sessions at the 45th annual meeting of the American Society of Hematology (ASH).
"We are very pleased to report that the consistency of the clinical findings continue to point to the potential applicability of our HSP technology to a multitude of cancers," said Garo H. Armen, PhD, chairman and CEO of Antigenics. "Our CML and NHL experience extend the use of our technology to hematological cancers in addition to solid tumors. If successfully developed ...
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Source: HighBeam Research, Data reported in trials of heat shock protein-based cancer vaccines.