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Hepatitis A vaccine does not promote atherogenesis in murine model.
2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The hepatitis A vaccine did not promote atherogenesis in a murine model.
According to recent research from the United States, "Our laboratory demonstrated that seropositivity to hepatitis A virus (HAV) independently predicts risk for coronary artery disease (CAD). As these findings are based only on the presence of HAV-specific antibodies and not infectious virus, this prompted questions regarding possible effects of HAV vaccines on CAD development."
"If seropositivity to HAV alone, resulting from HAV vaccination, leads to increased atherogenesis, this raises important issues regarding the benefit of protection against HAV infection vs the risk of developing CAD," said Mary Susan Burnett and colleagues at the MedStar Research Institute. "This study examines the effect of HAV vaccination on atherosclerosis development in a cholesterol-fed mouse model. Animals either received HAV vaccine, adjuvant, or saline. After 15 weeks, no significant differences were found in lesion area between the groups: HAV vaccine, 13,470 micrometer[superscript]2; adjuvant, 16,332 micrometer[superscript]2; and ...
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- Press release article from: PR Newswire March 4, 2005 700+ words
...of chronic viral hepatitis in the United...Strategic Research Institute announces the "Annual Viral Hepatitis in Drug Discovery...the area of viral hepatitis of North America...of Strategic Research Institute at gpascual...
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...line safety data from the study will be presented at the Viral Hepatitis in Drug Discovery and Development Meeting to be held in...Gastroenterology/Hepatology Research at the Duke Clinical Research Institute and Professor of Medicine at Duke University Medical Center...
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Viral hepatitis can cause as much damage to the...are at high risk of contracting viral hepatitis, compounding their risk of liver...excessive alcohol consumption and viral hepatitis have been known to cause cirrhosis...
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...World Hepatitis Day, more than 200 viral hepatitis groups around the world have planned...support for people living with chronic viral hepatitis B and C. In the United States, where...is especially urgent, the National Viral Hepatitis Roundtable (NVHR) today called on...
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...health resource use of patients with viral hepatitis in Tayside, Scotland, using record...Incidence and prevalence of known viral hepatitis in Tayside, survival of subjects diagnosed with viral hepatitis, and the health resource use with...
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...World Hepatitis Day, more than 200 viral hepatitis groups around the world have planned...support for people living with chronic viral hepatitis B and C (see also Hepatitis B Virus...is especially urgent, the National Viral Hepatitis Roundtable (NVHR) today called on...
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- Magazine article from: Bulletin of the World Health Organization Singh, J. Bhatia, R. Gandhi, J.C. Kaswekar, A.P. Khare, S. Patel, S.B. Oza, V.B. Jain, D.C. Sokhey, J. January 1, 1998 700+ words
...India, virtually all outbreaks of viral hepatitis are considered to be due to faeco...virus (HEV) (1-3). Outbreaks of viral hepatitis A have also been reported occasionally...been a sudden increase in cases of viral hepatitis B admitted to hospitals (4, 5...
Source: HighBeam Research, Hepatitis A vaccine does not promote atherogenesis in murine model.