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Helicobacter pylori vaccines spiral into the new millennium.

Vaccine Weekly

| January 07, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers review progress in the development of Helicobacter pylori vaccines is a recent issue of the journal Digestive and Liver Disease.

"This article reviews the current situation regarding research towards an effective human vaccine against Helicobacter pylori, with particular emphasis on developments in the new millennium. The mechanisms by which immunization of mice can affect Helicobacter colonization of mice remains a mystery, but may be related to immune mediated environmental changes. In particular, it is proposed that severe gastritis and T-cell mediated changes in mucin production can significantly impact upon H. pylori colonization," scientists in Australia report.

"Despite the potential influence of environmental factors, significant progress towards a truly effective vaccine may depend upon the induction of specific immune targeting of this pathogen," said P. Sutton and C. Doidge at the University of Melbourne. "This would ...

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Source: HighBeam Research, Helicobacter pylori vaccines spiral into the new millennium.

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