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2004 JAN 7 - (NewsRx.com & NewsRx.net) -- At its annual general and special meeting of shareholders, Neurochem, Inc., (NRMX) announced additional positive interim results on cognitive function as measured by the ADAS-cog test in mild-to-moderate Alzheimer Disease (AD) patients participating in its ongoing open-label phase II extension study.
Neurochem is reporting on patients who have completed 9 and also 12 months of treatment on the highest dose (300 mg daily) of the investigational product candidate Alzhemed.
"To date, the majority of our patients treated with Alzhemed have stabilized or improved. Even though the numbers are not statistically significant, the results are impressive and have never been seen before," stated Dr. Francesco Bellini, chairman and CEO of Neurochem.
"The results obtained are consistent with all our previously reported data. Neurochem has a strong commitment to develop much awaited solutions to treat AD. The Alzhemed program is one part of our multipronged approach against this disease. Continuing research efforts and discovery are on-going and include much more potent second and third generation compounds as well as a synthetic vaccine program to prevent and treat AD," he added.
Most recent results in 23 mild-to-moderate patients using the ADAS-cog test indicate that patients treated with Alzhemed have shown an average score of +2.0 points after 9 months, as opposed to +5.0 points on average in comparable historical controls in a longitudinal study with AD patients. Of that group, 14 mild AD patients showed a score after 9 months of treatment of -0.8 ...
Source: HighBeam Research, More positive results reported for Alzhemed.