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Cross-reactive H1N1 antibody responses to influenza vaccine reported.
2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Cross-reactive H1N1 antibody responses to a live attenuated influenza vaccine in children have implication for selection of vaccine strains.
According to published research from the United States, "Cross-reactive antibody responses of three trivalent, live attenuated intranasal influenza vaccine (FluMist) formulations containing three different H1N1strains (A/Texas/36/91, A/Shenzhen/227/95, and A/Beijing/262/95) were evaluated in initially seronegative children."
"FluMist containing A/Shenzhen/227/95 was more likely to induce cross-reactive hemagglutination inhibition (HAI) antibody against A/Texas/36/91 than against A/Beijing/262/95, and FluMist containing A/Beijing/262/95 induced low levels of cross-reactive HAI antibody against A/Shenzhen/227/95 and A/NewCaledonia/20/99," reported Min-Shi Lee and Chin-Fen Yang at MedImmune Vaccines. "The observed differences in HAI cross-reactivity seem to be partly related to ...
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Source: HighBeam Research, Cross-reactive H1N1 antibody responses to influenza vaccine reported.