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Passive and active cigarette smoke disrupts the mechanics of placental growth.
2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Passive and active cigarette smoke disrupts the mechanics of placental growth.
"Previously, we showed that maternal smoking harms human placental development by changing the balance between cytotrophoblast (CTB) proliferation and differentiation. To understand the mechanisms involved, we studied the effects of maternal smoking and in vitro exposure of CTBs to nicotine and on CTB expression of molecules that govern cellular responses to oxygen tension: the von Hippel-Lindau tumor suppressor protein (pVHL), the hypoxia-inducible transcription factors (HIFs), and the vascular endothelial growth factors (VEGFs)," stated researchers in the United States.
"We previously reported that hypoxia upregulates CTB pVHL expression (1). Here we show that in vitro exposure of CTBs to nicotine has the same effect," wrote O. Genbacev and colleagues, University California San Francisco, Department of Stomatology.
"Maternal smoking also dysregulated CTB expression of all three molecules. Remarkably, we found that passive exposure to cigarette smoke had many of the same ...
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...overlooked--imports of them all is French food. In downtown San Francisco, you'll find a thriving colony of comfortable French...986-5673. Live no-cover jazz, entwined with curls of cigarette smoke, is offered several nights a week at this authentic French...
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University of California, San Francisco Nonsmoking spouses of smokers...two University of California, San Francisco (UCSF), heart experts. The...waste dump," Glantz said. Cigarette smoke contains thousands of identified...
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...But our research also suggests that cigarette smoke substantially changes the immune response...We wanted to see whether and how cigarette smoke would change the inflammatory response...and colleagues tested the effects of cigarette smoke exposure on inflammation and immune...
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- Newspaper article from: Nutrition Health Review Cross, Caroll E. March 22, 1993 700+ words
...oxidized LDL is highly atherogenic. Cigarette smoke contains large quantities of free...sought to determine the effects of cigarette smoke on internally produced antioxidants...human LDL were exposed in vitro to cigarette smoke in order to duplicate the effects...
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- Magazine article from: Journal of Epidemiology & Community Health Etter, J-F Perneger, T V September 1, 2001 700+ words
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...reported chemical constituents of cigarette smoke using toxicological risk assessment...review of studies reporting yields of cigarette smoke constituents using standard ISO methods...synthesis: Data on 158 compounds in cigarette smoke were found. Of these, 45 were known...
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- Magazine article from: Environmental Health Perspectives Zhang, Jin Jiang, Shuguang Watson, Ronald R. October 1, 2001 700+ words
Sidestream cigarette smoke (SSCS) makes up about 85% of...lipid peroxidation, sidestream cigarette smoke. Environmental tobacco smoke...mixture of sidestream and mainstream cigarette smoke (SSCS and MSCS, respectively...
Source: HighBeam Research, Passive and active cigarette smoke disrupts the mechanics of...