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Hypertension is not the cause of increased CD risk during hormone replacement therapy.
2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Hypertension is not likely to underlie the heightened risk of heart disease associated with hormone replacement therapy.
"In recent studies, it has been found that postmenopausal hormonal therapy is associated with an increased incidence of cardiovascular disease," scientists in the United States explained.
However, "experimental studies suggest several potential mechanisms by which estrogens might decrease blood pressures, and estrogen administration attenuates hypertension in several animal models," noted J.M. Kotchen and colleagues at the Medical College of Wisconsin.
"In humans, although oral contraceptive agents are frequently associated with increases in blood pressure, blood pressure was not increased or was minimally increased in prospective clinical trials of hormone therapy in postmenopausal women," they reported.
"These observations suggest that the excess ...
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