AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
New antibody shows promise as agent for radioimmunotherapy of breast cancer.
2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Immunomedics, Inc., (IMMU) announced results from recent studies of the company's proprietary, humanized antibody, hRS7 (IMMU-112), which demonstrated that when the compound is labeled with iodine-131 using a new, residualizing method patented by Immunomedics, an almost 10-fold increase in uptake and retention was observed in human breast cancer growing in mice, as compared with results obtained with the same antibody conjugated with I-131 using conventional methodology.
The new approach resulted in a radiation dose to the tumor that was 4.3-times higher than the conventional radioiodinated antibody, and resulted in significantly greater inhibition of tumor growth in the animals.
"Complete remissions were observed in 5 of 11 mice, compared with only 1 of 11 in the group treated with the conventional radioiodinated antibody," observed Dr. S.V. Govindan, senior author of the paper and a ...
- Immunomedics Reports Clinical Trial Results for Potential New Test for Breast...
- Press release article from: PR Newswire October 23, 1998 700+ words
- Immunomedics' CEA-Scan(R...Suspected of Having Breast Cancer - MORRIS PLAINS, N...23 /PRNewswire/ -- Immunomedics, Inc. (Nasdaq: IMMU...use of CEA-Scan in breast cancer diagnosis was presented...
- IMMUNOMEDICS' CEA-SCAN DETECTS PRIMARY AND METASTATIC BREAST CANCER
- Press release article from: PR Newswire May 20, 1996 700+ words
...clinical trial with Immunomedics, Inc.'s...patients with breast cancer. Dr. Dutzu Rosner...emotional trauma." Immunomedics' chairman, Dr...patients with breast cancer, and although...product's use in breast cancer is under study...Phase III trials. Immunomedics ...
- Phase I/II trial results support potential use of Immunomedics' CEA-Scan(TM) in...
- Press release article from: Business Wire August 29, 1995 700+ words
...clinical trials in breast cancer patients in order...D., Chairman of Immunomedics. "We are also developing...therapy for metastatic breast cancer, based upon the excellent...CEA-Scan(TM). Immunomedics, Inc., based in...
- Immunomedics Awarded Over $1 Million in Government Grants - Breast Cancer and...
- Press release article from: PR Newswire September 2, 1999 700+ words
...PRNewswire/ -- Immunomedics, Inc. (Nasdaq...1,070,000. Breast Cancer Therapy According...therapeutic for metastatic breast cancer. This includes use...Cancer Institute and Immunomedics for the treatment...Chairman of the Board of Immunomedics, commented: "The...
- IMMUNOMEDICS ANNOUNCES POSITIVE CLINICAL RESULTS
- Press release article from: PR Newswire March 21, 1996 700+ words
...Detect and Stage Breast Cancer MORRIS PLAINS...PRNewswire/ -- Immunomedics, Inc. (Nasdaq...detection of breast cancer. These results...CEA-Scan in breast cancer patients later...chairman of Immunomedics. "When the...
- IMMUNOMEDICS AND MALLINCKRODT SIGN U.S. MARKETING AND DISTRIBUTION AGREEMENT...
- Press release article from: PR Newswire April 9, 1996 700+ words
...Chairman and CEO of Immunomedics. "The terms of this agreement allow Immunomedics to maintain an active...Americans annually. Lung and breast cancer indications for CEA...and anesthesiology. Immunomedics is a biopharmaceutical...
- IMMUNOMEDICS ANNOUNCES THIRD QUARTER 1993 FINANCIAL RESULTS IN LINE WITH...
- Press release article from: PR Newswire April 30, 1993 700+ words
...30 /PRNewswire/ -- Immunomedics, Inc. (NASDAQ: IMMU...ImmuRAID-CEA for lung and breast cancer, ImmuRAID(TM...president and CEO of Immunomedics. "This has been an active quarter for Immunomedics. We have reported significant...
- Immunomedics Awarded U.S. Patent for Humanized CEA Antibody Conjugates.
- Press release article from: PR Newswire January 15, 2004 700+ words
...with colorectal and breast cancer," commented Cynthia...Executive Officer of Immunomedics. Ms. Sullivan added...colorectal, pancreatic and breast cancer, with encouraging...remarked Ms. Sullivan. Immunomedics is a biopharmaceutical...