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Complete cross-reactivity found in Toxoplasma gondii isolates.

Vaccine Weekly

| December 17, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 DEC 17 - (NewsRx.com & NewsRx.net) -- An analysis involving 124 isolates of Toxoplasma gondii indicated that complete cross-reactivity means one vaccine is likely to protect against all of the isolates.

According to a study from the United States, "We tested 124 isolates of Toxoplasma gondii, as determined morphologically and by their ability to elicit antibodies in the dye test with the RH strain of Toxoplasma in mice. They were compared for their capacity to immunize CF-1 mice against isolate T-1, and T-1 immune mice for their capacity to resist each of the 123 other isolates."

"Of the 125 isolates, 52 had been isolated in the continental USA, 33 in Central America, 15 in Europe, 9 in Hawaii, 5 in Japan, 2 in Taiwan, 5 in Australia, 1 in Indonesia, 1 in Tunisia, and 1 was of unknown origin," stated Donald D. Smith and J. K. Frenkel at the University of Kansas. "Complete cross-immunity was found. This suggests ...

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Source: HighBeam Research, Complete cross-reactivity found in Toxoplasma gondii isolates.

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