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Test may predict adverse reaction to smallpox vaccinations.

Vaccine Weekly

| December 10, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The ability to predict which individuals would respond adversely to smallpox (variola major) vaccination may be possible, according to data presented by Malka Rais, MD, Georgetown University, at the 61st Annual Meeting of American College of Asthma, Allergy and Immunology in New Orleans.

Global eradication of smallpox ended the need for routine vaccination around 1972; however, the growing threat of bioterrorism may lead to its re-introduction for the purpose of protecting the population from an attack. Some individuals are in need of protection of the vaccine as those with compromised immune systems had, in the past, suffered serious side effects.

Rais captured a biochemical profile of 10 recipients of the smallpox vaccine in an effort to develop a predictive marker for side effect susceptibility. Blood specimens were taken from 10 ...

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