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Influenza mutants that can evade cytotoxic T cells will be those that spread.

Vaccine Weekly

| December 10, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Influenza mutants that can evade cytotoxic T cells will be those that spread.

According to a study from the United States, "a frenzied bout of evolution occurs every flu season, as viruses test the limits of the human immune system.

Variants that can evade attack by cytotoxic T cells gain a firm foothold in the viral population even if they confer an advantage in a low percentage of human hosts," wrote D. Wodarz and colleagues.

The researchers concluded: "A new mathematical model examines this unusual dynamic."

Wodarz and coauthors published the results of their research in Nature Medicine (Mutants escape from ...

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