AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Dengue 2 PDK-53 virus used as chimeric carrier for dengue vaccine.
2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The dengue 2 PDK-53 virus has been used as a chimeric carrier for tetravalent dengue vaccine development.
"Attenuation markers of the candidate dengue 2 (D2) PDK-53 vaccine virus are encoded by mutations that reside outside of the structural gene region of the genome. We engineered nine dengue virus chimeras containing the premembrane (prM) and envelope (E) genes of wild-type D1 16007, D3 16562, or D4 1036 virus within the genetic backgrounds of wild-type D2 16681 virus and the two genetic variants (PDK53-E and PDK53-V) of the D2 PDK-53 vaccine virus," scientists in the United States and Thailand report.
"Expression of the heterologous prM-E genes in the genetic backgrounds of the two D2 PDK-53 variants, but not that of wild-type D2 16681 virus, resulted in chimeric viruses that retained PDK-53 characteristic phenotypic markers of attenuation, including small plaque size and temperature sensitivity in LLC-MK2 cells, limited replication in C6/36 cells, and lack of neurovirulence in newborn ICR mice," stated Claire Y.-H. Huang and collaborators at the Centers for Disease Control and Prevention in the United States and Mahidol University-Salaya I Thailand.
"Chimeric D2/1, D2/3, and D2/4 viruses replicated efficiently in Vero cells and were immunogenic in AG129 mice," reported the investigators. "Chimeric D2/1 viruses protected adult AG129 mice against lethal DI ...
- Ciranova and TSMC Announce Strategic Partnership on Advanced PDK Technology.
- Press release article from: Business Wire March 24, 2009 700+ words
...development of advanced Process Design Kit (PDK) technology based on Ciranova's PyCell...integral part of TSMC's interoperable PDK development roadmap. Custom and analog...major issue at advanced process nodes, and PDK development and availability is a key bottleneck...
- DongbuAnam Offers Cadence Process Design Kit -- PDK-- to Speed Design of Analog...
- Press release article from: Business Wire March 2, 2005 700+ words
...Cadence Design Systems Process Design Kit (PDK) that speeds the design of analog functions...Cadence design automation software, the new PDK currently supports 0.18-micron design...of this year. "We chose Cadence as our PDK development partner because we wanted to...
- PDK Labs Inc. Signs Agreement to Go Private.
- Press release article from: Business Wire August 4, 2000 700+ words
...BUSINESS WIRE)--Aug. 4, 2000 PDK Labs Inc. (NASDAQ: PDKL, PDKLP) (the...merger (the "Merger Agreement") with PDK Acquisition Corp., a company owned by...Preferred Stock, excluding shares held by PDK Acquisition and its affiliates. The Merger...
- Artimi Successfully Completed Preliminary Interoperability Testing with Intel's...
- Press release article from: Business Wire March 13, 2006 700+ words
...interoperability testing with Intel's PDK. Artimi further announced the RTMI-150...and received UWB signals with the Intel PDK through several WiMedia PHYs during interoperability...Colin Macnab, CEO of Artimi. "Intel's PDK is considered the benchmarking tool in interoperability...
- USB Implementers Forum Releases USB 3.0 PDK.
- Magazine article from: Entertainment Close-up August 26, 2009 700+ words
...SuperSpeed USB) Peripheral Development Kit (PDK). The Forum said that the kit helps promote...emerging SuperSpeed USB ecosystem. The PDK is key to SuperSpeed USB development, and...systems developed in conjunction with the PDK engage in compliance testing, when available...
- PDK Labs authorizes reverse stock split.
- Press release article from: Business Wire July 20, 1995 700+ words
...WIRE)--July 20, 1995--The board of directors of PDK Labs Inc. ("PDK" or the "Company") (NASDAQ Symbol: PDKL) has authorized...for every 10 shares of common stock then outstanding. PDK Labs Inc. manufactures and distributes nationwide more...
- PDK Regency to build plant in China.(News)(Brief Article)
- Magazine article from: Home Textiles Today Sanfilippo, Michele June 27, 2005 700+ words
NEW YORK -- Next month PDK Regency will begin construction on a state...dyeing are done offsite in the region. PDK Regency no longer owns any domestic manufacturing...vice president, national sales manager of PDK Regency. PDK Regency's 6,800-square...
- PDK Labs Makes Announcement.
- Press release article from: Business Wire August 21, 1998 700+ words
...N.Y.--(BUSINESS WIRE)--Aug. 21, 1998--PDK Labs Inc. ("PDK" or the "Company") (NASDAQ Symbols: PDKL, PDKLP...variable expense growth relative to revenue growth. PDK Labs Inc. manufactures and distributes nationwide more...