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Role of adjuvants in vaccine immunogenicity reviewed.
2003 DEC 10 - (NewsRx.com & NewsRx.net) -- A researcher has reviewed the role and mechanisms of action of adjuvants in vaccine immunogenicity.
According to a study from the United States, "Inactivated vaccines require adjuvants to stimulate an immune response. The choice of adjuvant or immune enhancer determines whether the immune response is effective, ineffective, or damaging. Accordingly, there is a need for new adjuvants that stimulate the appropriate immunity, for example, T cell immunity for intracellular pathogens and cancer vaccines."
"In several adjuvants, the identification of chemical groups that interact with specific cell toll-like receptors (innate immunity) or receptors for costimulatory ligands (adaptive immunity), has enabled the establishment of structure-function relationships that are useful in the design of new adjuvants," stated Dante J. Marciani at Galencia ...
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Source: HighBeam Research, Role of adjuvants in vaccine immunogenicity reviewed.