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Eosinophilic-lymphocytic myocarditis proven after smallpox vaccination.
Vaccine Weekly
|
December 10, 2003 |
COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright
2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Researchers have confirmed the occurrence of eosinophilic-lymphocytic myocarditis after smallpox vaccination.
"Smallpox is an eradicated viral disease that has re-emerged as a potential bioterrorism threat. Smallpox vaccination was historically the most effective defense measure against wild smallpox virus. The risk of myopericarditis after vaccination might limit this option," investigators in the United States report.
"We report a case of biopsy-proven eosinophilic-lymphocytic myocarditis diagnosed in vivo with histological evidence for eosinophil-mediated cardiac myocyte necrosis shortly after smallpox vaccination," said Joseph G. Murphy and colleagues at the Mayo Clinic. "Furthermore, we report a beneficial hemodynamic response to high-dose corticosteroids. A better understanding of the aberrant immune mechanism of myocyte injury after ...
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Source: HighBeam Research, Eosinophilic-lymphocytic myocarditis proven after smallpox...