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Soy isoflavones help postmenopausal women with low bone mass retain density.
2003 DEC 4 - (NewsRx.com & NewsRx.net) -- Soy isoflavones help postmenopausal women with low bone mass retain density.
"Animal studies have shown that soy isoflavones have an effect in preventing estrogen-related bone loss, but few data are available in humans, especially in the Asian populations. This double-blind, placebo-controlled, randomized trial examined the effects of soy isoflavones on bone loss in postmenopausal Chinese women, aged 48 - 62 years (yr)," scientists in the Peoples Republic of China reported.
"Two hundred and three eligible subjects were randomly assigned to three treatment groups with daily doses of placebo (1 g starch; n = 67), mid-dose (0.5 g starch, 0.5 g soy extracts, and approximately 40 mg isoflavones; n = 68), and high dose (1.0 g soy extracts and approximately 80 mg isoflavones; n = 68). All were given 12.5 mmol (500 mg) calcium and 125 IU vitamin D-3. Bone mineral density (BMD) and bone mineral content (BMC) of the whole body, spine, and hip were measured using dual energy x-ray absorptiometry at baseline and 1 yr post treatment," said Y.M. Chen and colleagues, Chinese University of Hong Kong, Department of Community and Family Medicine.
"Both univariate and multivariate analyses showed that women in the high dose group had mild, but statistically significantly, higher favorable change rate in BMC at the total hip and trochanter (p
"In conclusion, soy ...
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