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Menstrual cycle influences baroreflex heart rate control.
2003 DEC 4 - (NewsRx.com & NewsRx.net) -- Baroreflex regulation of cardiac activity is influenced by the menstrual cycle in women.
Researchers in Japan conducted a study "to determine baroreflex control of heart rate (HR) to hypotensive and hypertensive stimuli during the early follicular (EF), preovulation (PreOV), and midluteal (ML) phases of the menstrual cycle, and to test the hypothesis that cardiovagal reflex responses to hypertensive stimuli would be altered depending on the plasma estradiol levels in healthy women."
"In addition, these results were compared with those of male volunteers," noted M. Tanaka and coauthors at Akita University.
"Fifteen healthy women with regular menstrual cycles and thirteen male volunteers were recruited," they explained. "Cardiovagal baroreflex sensitivity was defined as the slope of the linear portion relating R-R interval and systolic blood pressure triggered by bolus injections of nitroprusside and phenylephrine, from the overshoot phase of the Valsalva maneuver, and during spontaneous fluctuations."
"Three measurements were averaged in each test as a representative at each phase, and the order of phases was counterbalanced," according to the report. "Baroreflex sensitivities by the phenylephrine pressor test and Valsalva maneuver during the PreOV phase were significantly greater than those during the EF and ML phases, but were similar to those of men."
"Depressor test ...
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