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Role of adipocytokines in anorexia nervosa reviewed.
2003 DEC 4 - (NewsRx.com & NewsRx.net) -- Researchers review the role of the two adipocytokines, leptin and adiponectin, in anorexia nervosa in a recent issue of Hormone and Metabolic Research.
"Adipose tissue secretes a large number of physiologically active peptides that often share structural properties with cytokines, and are therefore collectively referred to as 'adipocytokines'. Some of these are almost exclusively secreted by adipose tissue. Leptin, adiponectin, and resistin are specific fat-derived hormones that affect fuel homeostasis and insulin action, and may also be involved in hematopoiesis and immune functions," scientists in Belgium report.
"Anorexia nervosa is characterized by chronic self-starvation and severe weight loss, mainly at the expense of adipose tissue," said Sonia M. Brichard and colleagues at the University of Louvain. "Starvation-induced depletion of fat stores is accompanied by alterations of circulating adipocytokines. Plasma leptin and likely resistin levels are decreased in anorectic patients, while plasma adiponectin levels are increased. These alterations may have potential ...
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Source: HighBeam Research, Role of adipocytokines in anorexia nervosa reviewed.