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2003 DEC 4 - (NewsRx.com & NewsRx.net) -- Oregon Health & Science University (OHSU) researchers have presented study findings that help explain the relationship between weight gain and menopause.
The study helps demonstrate how female hormones appear to play a major role in America's obesity epidemic. The findings may also provide new methods for fighting obesity. Additional data from the research relate to the long-held belief that food eaten late at night may lead to weight gain and to changes in metabolism with age.
The results of the study were presented Judy Cameron, PhD, and her colleagues on November 12, 2003, at the annual Society for Neuroscience Meeting, held this year in New Orleans, Louisiana.
"Perhaps most importantly, this research pertains to the worsening obesity epidemic [in the U.S.]. Currently about 30% of Americans are considered obese. In addition, significant weight gain has been tied to various serious health conditions, including diabetes, stroke, heart disease, joint problems, and various forms of cancer," explained Cameron, a scientist in the divisions of Reproductive Sciences and Neuroscience at the OHSU Oregon National Primate Research Center.
"In women, it has been demonstrated that major weight increases often occur during menopause, the time in a woman's life in which cyclic ovarian function ends and the ovarian hormones estrogen and progesterone decline. The goal of this research was to determine whether, and to what extent, the decline in these hormones have an effect on body weight in an effort to better understand and proactively treat obesity."
To conduct this research, Cameron, along with graduate student Elinor Sullivan and other colleagues, studied 47 adult female monkeys. Nineteen of the monkeys had their ovaries surgically removed, a common procedure that results in a drop of estrogen and progesterone levels, much like menopause.
While monkeys, like humans, go through menopause naturally during ...