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First human trial of West Nile vaccine to begin.
2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Acambis (ACAM) announced the start of a phase I trial of its investigational vaccine against West Nile virus, ChimeriVax-West Nile.
Since it was first identified in New York in 1999, the West Nile virus has swept through 45 U.S. states, causing disease in more than 12,000 people and resulting in the deaths of several hundred individuals. In 2003 alone, it has affected more than 8,200 people and caused 182 deaths. The virus has also spread south to Central America and the Caribbean, and north into Canada where it has been identified in seven provinces.
Acambis used its proprietary ChimeriVax technology to develop the investigational ChimeriVax-West Nile vaccine and has conducted a series of successful pre-clinical studies on the vaccine. Acambis has now started a phase I clinical trial in humans.
The trial is being conducted in Lenexa, Kansas under a U.S. Food and Drug Administration Investigational New Drug application. The trial is a randomized, double-blind out-patient study in 60 healthy adult volunteers. It will test the safety, tolerability and immunogenicity of the ChimeriVax-West Nile ...
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- Press release article from: PR Newswire September 3, 2003 700+ words
...for the project. Acambis will provide its...investigational ChimeriVax-West Nile vaccine, qualified...severe disease. Acambis' vaccine, ChimeriVax-West Nile, has been developed...protecting against West Nile virus. Acambis plans to begin a...
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...Press Release) Acambis plc is to present...clinical data on its West Nile vaccine, ChimeriVax...Dr Juan Arroyo, Acambis' Project Leader for ChimeriVax-West Nile, is to give a...with wild-type West Nile virus. Acambis has developed this...
Source: HighBeam Research, First human trial of West Nile vaccine to begin.