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P. falciparum SERA protein peptide analogues protect against malaria.
2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria.
According to recent research from Colombia, "Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution."
"Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did not present protection against the disease in these monkeys," reported Marcia Cubillos and collaborators at the Fundacion Instituto de Inmunologia de Colombia (FIDIC) and Universidad Nacional de Colombia. "Results showed a relationship between these peptides' secondary structure and their function as immunogen against ...
- Prolactin-releasing peptide analogues may help clarify multiple functions.
- Newspaper article from: Pain & Central Nervous System Week February 10, 2003 700+ words
2003 FEB 10 - (NewsRx.com & NewsRx.net) -- According to a study from Italy, "Prolactin-releasing peptides (PrRPs) are two novel bioactive peptides of 20 and 31 residues, dubbed respectively PrRP20 and PrRP31, isolated from bovine hypothalamic tissues as ligands of the orphan seven-transmembrane
- Neurocrine Biosciences obtains United States patent.(Brief Article)
- Newspaper article from: BIOTECH Patent News April 1, 2002 700+ words
...Diego, CA) has patented peptide analogues of human myelin basic...99. Residue 91 of the peptide analogues is altered from the L...Pharmaceutical compositions of the peptide analogues are provided. In addition...
- Scientists Develop 'Super Peptide' That Kills Candida Albicans - Fungus...
- Press release article from: PR Newswire February 20, 2003 700+ words
...study, "Novel alpha-Melanocyte Stimulating Hormone Peptide Analogues with High Candidacidal Activity," is scheduled to appear...albicans through design, synthesis and testing of novel peptide analogues in which several modifications were made. Because previous...
- Scientists develop 'Super Peptide' that kills Candida albicans - fungus...
- News wire article from: Asia Africa Intelligence Wire February 20, 2003 700+ words
...study, "Novel alpha-Melanocyte Stimulating Hormone Peptide Analogues with High Candidacidal Activity," is scheduled to appear...albicans through design, synthesis and testing of novel peptide analogues in which several modifications were made. Because previous...
- Scientists develop 'Super Peptide' that kills Candida albicans - Fungus...
- Press release article from: PR Newswire February 20, 2003 700+ words
...study, "Novel alpha-Melanocyte Stimulating Hormone Peptide Analogues with High Candidacidal Activity," is scheduled to appear...albicans through design, synthesis and testing of novel peptide analogues in which several modifications were made. Because previous...
- Company acquires new peptide to increase its diabetes portfolio.
- Newspaper article from: Biotech Week February 19, 2003 700+ words
...announced for the treatment of type II diabetes in recent months. The first involving several GLP-1 (glucagon-like peptide) analogues has emerged from internal research at Theratechnologies; one of these GLP-1 peptides will be selected for development...
- Serine repeat antigen genes essential for blood-stage parasite growth.
- Newspaper article from: Genomics & Genetics Weekly February 7, 2003 700+ words
...Miller and colleagues published the results of their study in the Journal of Biological Chemistry (A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle. J Biol Chem, 2002;277(49):47524...
- XENOME ENTERS INTO JOINT RESEARCH COLLABORATION.
- News wire article from: AsiaPulse News November 27, 2007 700+ words
...library for new drug discovery. This library complements additional peptide libraries at Xenome comprised of other novel peptide analogues. Further information: Lewis Lee Director & CEO Xenome Ltd Tel: +61 7 3720 8055 E-mail: lewis.lee@xenome...
- Novel methods of modification and production of peptides and proteins for...
- News wire article from: Chemical Business Newsbase December 31, 2006 700+ words
...phase peptide using an alkoxysilyl moiety as an interim carboxyl-protecting group. This new synthetic method can prepare peptide analogues containing C-terminal modifications (like esters, thioesters and alcohols) and peptides having peptide bond modifications...
- Louisiana State University Health Sciences Center Research Sheds Light on SARS.
- News wire article from: Ascribe Higher Education News Service May 2, 2003 700+ words
...function," said Dr. Gallaher, "so we know quite a bit about the SARS coronavirus. We are designing drugs, such as peptide analogues or peptidomimetics of this structure, that are predicted to have significant antiviral activity." (Peptidomimetics...
Source: HighBeam Research, P. falciparum SERA protein peptide analogues protect against malaria.