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Researchers reveal essential component of immunity to liver-destroying virus.
2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Researchers at Columbus Children's Research Institute (CCRI) on the campus of Columbus Children's Hospital have identified a key component of protective immunity against the hepatitis C virus, the major cause of chronic liver disease and transplantation in the United States.
The study found that successful control of hepatitis C infection required close cooperation between two types of white blood cells know as CD4+ "helper" and CD8+ "killer" T lymphocytes. The findings, published in Science, indicate that the immune system is unable to eliminate the virus without the CD4+ T lymphocytes.
"Our goal is to understand how a person's immune response determines the outcome of the hepatitis C infection," said Christopher M. Walker, PhD, director of the Center for Vaccines and Immunity at CCRI on the campus of Columbus Children's Hospital and professor of pediatrics at the Ohio State University College of Medicine and Public Health. "Approximately 70% of individuals exposed to hepatitis C become lifelong carriers of the virus. The remaining individuals successfully contain the infection and appear to have ...
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...Tubbs and colleagues, Columbus Children's Hospital (see also...contact R.S. Tubbs, Columbus Children's Hospital, Sect...07030, USA. Keywords: United States, Birmingham, Anatomy, Columbus Children's Hospital. This...
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...Myers and colleagues, Columbus Children's Hospital. The researchers...contact W.P. Myers, Columbus Children's Hospital, Boston...England. Keywords: United States, Boston, Malaria, Columbus Children's Hospital. This article...
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...and colleagues, Columbus Children's Hospital (see...P. Kozakewich, Columbus Children's Hospital, Dept...USA. Keywords: United States, Boston, Dermatology...Hemangioma, Pathology, Columbus Children's Hospital. This...
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...and colleagues, Columbus Children's Hospital. The...contact O. Commowick, Columbus Children's Hospital, Dept...USA. Keywords: United States, Boston, Life Sciences...Imaging Science, Columbus Children's Hospital. This...
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- Newspaper article from: Genomics & Genetics Weekly March 27, 2009 700+ words
...investigators in the United States report (see...colleagues, Columbus Children's Hospital...Mccarthy, Columbus Children's Hospital...Keywords: United States, Boston...Genetics, Columbus Children's Hospital...
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- Newspaper article from: Science Letter July 7, 2009 700+ words
...and colleagues, Columbus Children's Hospital (see...contact J. Steen, Columbus Children's Hospital, FM...USA. Keywords: United States, Boston, Mass Spectrometry...Proteome Research, Columbus Children's Hospital. This...
Source: HighBeam Research, Researchers reveal essential component of immunity to...