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Technical issues in construction of nucleic acid vaccines reviewed.
2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Researchers review the technical issues in construction of nucleic acid vaccines in a recent issue of the journal Methods.
"Delivery of antigen-encoding genes by nucleic acid vaccine vectors offers tremendous advantages in power and flexibility over conventional antigen delivery systems. Of the many forms of nucleic acid vaccine that can be constructed, circular DNA plasmids are the simplest," investigators in England report.
"In this article, we consider the components that make up a generic DNA plasmid vaccine," said Peter F. Ertl and Lindy L. Thomsen at GlaxoSminthKline. "We discuss some of the issues encountered when optimizing these vectors to exploit their potential for in vivo expression and presentation of antigens ...
- Technical issues in construction of nucleic acid vaccines reviewed.
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...technical issues in construction of nucleic acid vaccines in a recent issue of the journal...antigen-encoding genes by nucleic acid vaccine vectors offers tremendous...Technical issues in construction of nucleic acid vaccines. Methods, 2003;31(3...
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